Small study aims to predict which breast cancer patients benefit from immunotherapy
NCT ID NCT05877859
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is looking at how the immune system responds in people with early-stage triple negative breast cancer who receive standard chemotherapy plus the immunotherapy drug pembrolizumab before surgery. The goal is to see if certain immune markers in the blood or tumor tissue can predict whether the cancer will completely disappear after treatment. Only 10 participants will be enrolled, and the study does not test a new treatment but rather monitors responses to the current standard of care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pembrolizumab (a type of immunotherapy) given with standard chemotherapy
- What this could lead to
- If successful, this study could help doctors understand which patients with early-stage triple negative breast cancer are most likely to benefit from adding immunotherapy to chemotherapy before surgery.
- What could go wrong
- This is a very small pilot study with only 10 participants, so results may not apply to all patients. It is designed to gather information, not to prove a new treatment works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Emory University/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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