Fingernail moons may reveal who responds to breast cancer therapy

NCT ID NCT07590570

Ongoing Knowledge-focused Sponsor: Wenjin Yin Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the small white moons at the base of fingernails (lunula) can predict how well breast cancer patients respond to chemotherapy before surgery. Researchers will track 188 patients to see if lunula status is linked to tumor disappearance and side effects. The goal is to find a simple, non-invasive way to personalize treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: neoadjuvant therapy (chemotherapy before surgery)
What this could lead to: If successful, this could help doctors predict which breast cancer patients will benefit most from neoadjuvant therapy, personalizing treatment.
What could go wrong: This is an observational study, not a treatment trial. The link between lunula status and outcomes is unproven and may not lead to any change in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER INVASIVE

Contacts and locations

Locations

Renji Hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, 200127, China

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