How often should you get up from your chair? new study aims to find out

NCT ID NCT05353322

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing different combinations of how often and for how long people should interrupt prolonged sitting to improve blood pressure and blood sugar. Over 300 adults will take part in a 9-hour lab visit where they sit and take short walking breaks at various frequencies and durations. The goal is to find the smallest effective dose of activity that provides cardiometabolic benefits, which could inform future public health guidelines.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
walking breaks
What this could lead to
If successful, this study could provide clear, evidence-based recommendations on how often and for how long people should stand or walk to improve heart health and blood sugar.
What could go wrong
This is an early-phase, lab-based study with healthy adults, so results may not apply to people with chronic conditions or in real-world settings. The benefits are short-term and may not translate into long-term health improvements.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Insulin Resistance Motor Activity Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Behavioral Cardiovascular Health

    RECRUITING

    New York, New York, 10032, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.