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Mind over matter: brain implant lets paralyzed patients control computers

NCT ID NCT00912041

Recruiting now Disease control Sponsor: Leigh R. Hochberg, MD, PhD. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests the safety and feasibility of the BrainGate2 system, a brain-computer interface. Tiny sensors are placed in the brain area that controls movement, allowing people with tetraplegia (paralysis of all four limbs) to control a computer cursor or other assistive devices using their thoughts alone. Up to 27 participants with conditions like spinal cord injury or ALS will be enrolled, and the study focuses on safety and proof of concept.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
BrainGate2 neural interface system (implanted brain sensors connected to a computer)
What this could lead to
If successful, this could lead to a way for people with paralysis to control computers, wheelchairs, or other assistive devices using only their thoughts.
What could go wrong
This is a very early feasibility study with only 27 participants. The device requires brain surgery, which carries risks like infection or bleeding. It may not work for everyone or lead to a widely available product.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis brain stem infarction locked-in syndrome muscular dystrophy quadriplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS BRAIN STEM INFARCTIONS LOCKED-IN SYNDROME MUSCULAR DYSTROPHY SPINAL CORD INJURIES TETRAPLEGIA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

  • Emory University School of Medicine

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Providence VA Medical Center

    RECRUITING

    Providence, Rhode Island, 02908, United States

  • Stanford University School of Medicine

    RECRUITING

    Stanford, California, 94305, United States

  • University of California, Davis

    RECRUITING

    Sacramento, California, 95817, United States

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