New brain stimulation study aims to personalize depression treatment for veterans

NCT ID NCT06548113

Not yet recruiting Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will measure how different types of transcranial magnetic stimulation (TMS) change brain activity in 250 military veterans with major depressive disorder. Researchers hope to use this information to develop more personalized brain stimulation treatments. Participants will undergo TMS sessions while their brain activity is recorded with EEG.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If successful, this could lead to more personalized and effective brain stimulation treatments for depression in veterans.
What could go wrong: This is an early-stage observational study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

VA Palo Alto Health Care System, Palo Alto, CA

Palo Alto, California, 94304-1207, United States

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