Scans reveal brain changes in gaucher and Parkinson's families

NCT ID NCT00302146

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 30 times

Summary

This study used PET and MRI scans to compare brain dopamine function in people with Gaucher disease, Parkinson's disease, or a family history of these conditions, against healthy volunteers. Researchers aimed to detect early brain changes linked to glucocerebrosidase gene mutations. The study involved 64 adults aged 21 and older and did not test any treatment.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.