Brain scans reveal sex differences in Smokers' glutamate levels

NCT ID NCT05279053

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how smoking affects a brain chemical called glutamate in men versus women. Researchers scanned the brains of 58 smokers after not smoking overnight and after their first cigarette of the day. They also measured hormone levels in women to see if hormones influence brain chemistry. The goal was to better understand sex differences in smoking addiction, not to test a treatment.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Coitus nicotine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCLA Semel Institute

    Los Angeles, California, 90095, United States

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