Could a gut infection trigger food allergies in IBS?

NCT ID NCT06413004

Recruiting now Knowledge-focused Sponsor: Magnus Simrén Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study investigates whether a gut infection called Brachyspira causes IBS symptoms by making the immune system overreact to certain foods. Researchers will use advanced imaging to identify which foods trigger reactions in the gut. Participants will eliminate those foods for four weeks, then reintroduce them, while their symptoms are tracked. The goal is to understand whether treating the infection or avoiding trigger foods could help manage IBS.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Elimination and re-introduction of food items identified by CLE or COLAP
What this could lead to: If successful, this could reveal a new cause of IBS symptoms and point toward personalized dietary treatments.
What could go wrong: This is an early exploratory study with no treatment being tested; results may not lead to a clear or broadly applicable therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FOOD SENSITIVITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Food Intolerance irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FOOD SENSITIVITY IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

Mag-tarmlab, Dept of Internal Medicine, Sahlgrenska University Hospital
RECRUITING

Gothenburg, 413 45, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.