New hope for brain cancer: experimental combo targets glioblastoma

NCT ID NCT04752813

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding the experimental drug BPM31510 (with vitamin K1) to standard radiation and chemotherapy can help people with newly diagnosed glioblastoma live longer without their cancer growing. About 50 adults with this aggressive brain tumor will receive the combination. The goal is to see if the treatment improves progression-free survival and overall survival.

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Conditions

The condition(s) this trial relates to.

glioblastoma glioma susceptibility 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Inova

    Fairfax, Virginia, 22037, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • Sansum Clinic

    Santa Barbara, California, 93105, United States

  • Stanford University Cancer Center

    Palo Alto, California, 94305, United States

  • Texas Oncology

    Austin, Texas, 78705, United States

  • UT Health San Antonio Mays Cancer Center

    San Antonio, Texas, 78229, United States

  • Valley Health

    Ridgewood, New Jersey, 07450, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • Virginia Oncology Associates

    Norfolk, Virginia, 23502, United States