Botox in the womb: a new hope for crippling period pain?

NCT ID NCT06995287

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting botulinum toxin (Botox) into the uterine muscle can reduce severe period pain in women who haven't found relief from standard treatments. 222 women will receive either Botox or a placebo injection via a small camera inserted into the uterus. The main goal is to see if women feel significantly better after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum toxin (Botox)

What this could lead to

If it works, this could offer a new, long-lasting pain relief option for women with severe period pain who haven't been helped by standard treatments.

What could go wrong

This is still an experimental procedure with risks from the injection itself. The placebo group may also show improvement, and the effect may not last beyond a few months.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY DYSMENORRHEA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Angers

    NOT_YET_RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Brest

    NOT_YET_RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Lille

    NOT_YET_RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Nantes

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Rennes

    NOT_YET_RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinique Brétéché

    NOT_YET_RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinique axium / Centre resilience

    NOT_YET_RECRUITING

    Aix-en-Provence, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital de la Croix-Rousse

    NOT_YET_RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••