Botox during prostate surgery: a promising combo that never got tested
NCT ID NCT05393921
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This study aimed to see if giving Botox injections into the bladder at the same time as HoLEP prostate surgery could improve urinary symptoms in men with an enlarged prostate and overactive bladder. The plan was to compare symptom scores and urine flow between men who got both treatments and those who had surgery alone. However, the study was withdrawn before any participants were enrolled, so no conclusions can be drawn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botox (onabotulinumtoxinA) injection into the bladder
- What this could lead to
- If it worked, this approach could offer faster and more complete relief from urinary symptoms after prostate surgery, reducing the need for a second procedure.
- What could go wrong
- The study was withdrawn before enrolling anyone, so no results are available. Combining treatments may increase risks like infection or urinary retention without clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UH Brainard Medical Bldg
Lyndhurst, Ohio, 44124, United States
-
UH Regional Hospitals - Richmond Campus
Richmond Heights, Ohio, 44143, United States
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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