Botox shot during prostate op eases overactive bladder

NCT ID NCT07554989

First seen May 02, 2026 · Last updated Jun 19, 2026 · Updated 6 times

Summary

This study looked at 70 men with an enlarged prostate and overactive bladder symptoms. Some received a Botox injection into the prostate during surgery, while others took standard medication after surgery. The Botox group showed better symptom scores at 12 weeks, suggesting a potential benefit. However, the study is small and retrospective, so more research is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Taksim Egitim Ve Arastirma Hastanesi

    Istanbul, 34433, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Botulinum toxin-A (Botox) injection into the prostate

What this could lead to

If successful, this could offer a more effective one-time treatment for overactive bladder symptoms in men undergoing prostate surgery, reducing the need for long-term medication.

What could go wrong

This is a small retrospective study (70 patients) with no randomization, so results may not apply to everyone. The injection adds a procedure with potential risks like pain or infection, and long-term benefits beyond 12 weeks are unknown.

Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia bladder neck obstruction overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.