Botox shot during prostate op eases overactive bladder

NCT ID NCT07554989

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 70 men with an enlarged prostate and overactive bladder symptoms. Some received a Botox injection into the prostate during surgery, while others took standard medication after surgery. The Botox group showed better symptom scores at 12 weeks, suggesting a potential benefit. However, the study is small and retrospective, so more research is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Botulinum toxin-A (Botox) injection into the prostate
What this could lead to
If successful, this could offer a more effective one-time treatment for overactive bladder symptoms in men undergoing prostate surgery, reducing the need for long-term medication.
What could go wrong
This is a small retrospective study (70 patients) with no randomization, so results may not apply to everyone. The injection adds a procedure with potential risks like pain or infection, and long-term benefits beyond 12 weeks are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Taksim Egitim Ve Arastirma Hastanesi

    Istanbul, 34433, Turkey (Türkiye)

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