Teens with Crohn's may have hidden bone changes, MRI study hopes to find out

NCT ID NCT04508088

Recruiting now Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses MRI scans to look at bone marrow fat in teenagers newly diagnosed with Crohn's disease, comparing them to healthy teens. The goal is to understand if Crohn's affects bone health early on. Researchers will also measure bone density using other imaging methods. The study involves 92 participants and aims to uncover how the disease impacts bones from the start.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how Crohn's disease affects bone health early on, pointing toward ways to prevent bone problems in young patients.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to direct changes in care, and results might not apply to all patients with Crohn's.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE INFLAMMATORY BOWEL DISEASE

Contacts and locations

Locations

Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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