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New bone putty could strengthen dental implants in the smile zone

NCT ID NCT07700706

Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This trial tests two bone-grafting materials—silicate-added β-TCP putty and extended sticky bone—against no grafting for filling gaps around dental implants placed immediately after tooth extraction in the front upper jaw. Researchers will measure implant stability and bone loss using special devices and scans. The goal is to find the best approach for preserving bone and tissue in the visible smile area.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silicate-added β-TCP putty and extended sticky bone (bone-grafting materials)
What this could lead to
If successful, this could identify a better way to fill bone gaps around dental implants, improving implant stability and long-term success.
What could go wrong
This is a small, early-stage trial with only 72 participants, so results may not apply to everyone. Bone grafting carries risks like infection or graft failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

72 people

The number who actually took part.

Started

Dec 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with non-restorable teeth in maxillary esthetic zone requiring dental extraction. * Age range: from18 to 50 years. * Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration. * Jumping gap more than 2mm. * Patients with good oral hygiene. * Patients willing to participate in the study's follow-up intervals. Exclusion Criteria: * Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement. * Alcohol or drug abuse. * Smokers. * Patients with systemic diseases that absolutely contraindicate implant placement (bleeding disorders, immunosuppression,…etc.) * Pregnancy. * Patients with para-functional habits (bruxism and clenching). * Lack of motivation or inability to maintain good oral hygiene.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone grafting Customized healing abutment Guided immediate implant placement Provisional crown Tooth loss in the esthetic zone requiring immediate implant placement

Contacts and locations

Locations

  • Faculty of Dentistry Mansoura University

    Al Mansurah, Dakahlia Governorate, Egypt

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