New scan may spare bladder cancer patients from surgery

NCT ID NCT04321707

Completed Diagnosis Sponsor: Jørgen Bjerggaard Jensen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special type of PET/MR scan (using radioactive water) can accurately tell if bladder cancer has been completely eliminated by chemotherapy. 13 patients with muscle-invasive bladder cancer were scanned before and after chemotherapy, and the results were compared to the actual tissue removed during surgery. The goal is to find a non-invasive way to identify patients who are cancer-free and might safely avoid bladder removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 15O-H2O PET/MR scan
What this could lead to: If successful, this scan could help identify bladder cancer patients who are cancer-free after chemotherapy, allowing them to keep their bladder instead of having it removed.
What could go wrong: This is a very small, early study with only 13 participants. The scan may not be accurate enough to replace standard surgery, and more research is needed.

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Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLADDER CANCER

Contacts and locations

Locations

Department of Urology, Aarhus University Hopsital

Aarhus, 8000, Denmark

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