New MRI method could speed up bladder cancer diagnosis

NCT ID NCT05779631

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new diagnostic approach—using an MRI plus a same-day biopsy—against the standard procedure (TURBT) for diagnosing muscle-invasive bladder cancer. Researchers will enroll 360 adults suspected of having this aggressive cancer. The goal is to see if the new method leads to faster treatment and better outcomes, such as longer survival without the cancer spreading.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mpMRI plus same-day cystoscopic bladder biopsy
What this could lead to
If successful, this could replace the standard two-step diagnosis with a faster, single-day procedure, potentially improving survival by starting treatment sooner.
What could go wrong
This is a diagnostic study, not a treatment trial. The MRI approach may not prove more effective than current methods, and some patients may still need additional procedures.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amsterdam UMC, location AMC

    RECRUITING

    Amsterdam, Netherlands

  • Amsterdam UMC, location VUmc

    RECRUITING

    Amsterdam, Netherlands

  • Antoni van Leeuwenhoek - Netherlands Cancer Institute

    RECRUITING

    Amsterdam, Netherlands

  • Bernhoven ziekenhuis

    RECRUITING

    Uden, Netherlands

  • Canisius Wilhelmina Ziekenhuis

    RECRUITING

    Nijmegen, Netherlands

  • Erasmus Medical Center

    NOT_YET_RECRUITING

    Rotterdam, Netherlands

  • Jeroen Bosch ziekenhuis

    RECRUITING

    's-Hertogenbosch, Netherlands

  • Maasziekenhuis Pantein

    RECRUITING

    Boxmeer, Netherlands

  • Meander MC

    NOT_YET_RECRUITING

    Amersfoort, Netherlands

  • Medisch Spectrum Twente

    NOT_YET_RECRUITING

    Enschede, Netherlands

  • OLVG

    RECRUITING

    Amsterdam, Netherlands

  • Radboud university medical center

    RECRUITING

    Nijmegen, Netherlands

  • Rijnstate ziekenhuis

    RECRUITING

    Arnhem, Netherlands

  • St. Antonius ziekenhuis

    RECRUITING

    Nieuwegein, Netherlands

  • Treant

    NOT_YET_RECRUITING

    Emmen, Netherlands

  • University Medical Center Utrecht

    RECRUITING

    Utrecht, Netherlands

  • VieCuri medisch centrum

    RECRUITING

    Venlo, Netherlands

  • Ziekenhuis Gelderse Vallei

    RECRUITING

    Ede, Netherlands

  • Ziekenhuisgroep Twente

    RECRUITING

    Almelo, Netherlands

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