Brain oxygen dips linked to injury markers in severe TBI
NCT ID NCT04565119
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study looks at 300 adults with severe traumatic brain injury to see how low brain oxygen levels affect certain proteins in the blood, known as biomarkers. Researchers will measure these proteins to better understand brain damage and recovery. The study does not test any new treatment but aims to improve knowledge for future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better understand how low oxygen levels in the brain after injury affect recovery, potentially leading to improved monitoring and treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test any new therapy, and the findings may not lead to immediate changes in patient care.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, 19104, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States