Portuguese study reveals how benralizumab works in real life for severe asthma
NCT ID NCT07159295
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked back at medical records of 74 adults in Portugal with severe eosinophilic asthma who were treated with benralizumab. Researchers wanted to describe patient characteristics, treatment patterns, and outcomes in real-world settings. The study did not test a new treatment but gathered information to understand how benralizumab is used outside of clinical trials.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- benralizumab
- What this could lead to
- If successful, this study could help doctors understand how well benralizumab works in everyday practice for severe asthma patients in Portugal.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to other countries or populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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74 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Nov 2022
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Severe eosinophilic asthma patients aged 18 and above, treated with benralizumab and who have had their first benralizumab dose between July 2019 and October 2020 and who have at least 1 benralizumab injection and with at least 3 months follow-up data from the first injection.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults patients with severe asthma treated with benralizumab, who had their first benralizumab dose between July 2019 and October 2020 * Patients who have at least 1 benralizumab injection and with at least 3 months follow-up data from the first injection. * Give voluntary signed informed consent Exclusion Criteria: * Currently receiving benralizumab or any other biologic drug for the treatment of asthma in a clinical trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHTMAD
Vila Real, 5000-508, Portugal
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CHUA
Faro, 8000-368, Portugal
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CHUA
Portimão, 8500-338, Portugal
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CHUC - Imunoalergologia
Coimbra, 3000 -076, Portugal
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CHUC - Pneumologia
Coimbra, 3000 -076, Portugal
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CHUSJ - Imuno
Porto, 4200 - 319, Portugal
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CHUSJ - Pneumo
Porto, 4200 - 319, Portugal
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CHVNGE
Vila Nova de Gaia, 4430 - 999, Portugal
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Chln - Hsm
Lisbon, 1649-035, Portugal
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Chuln - Hsm
Lisbon, 1649-035, Portugal
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Chusj - Cri
Porto, 4200-319, Portugal
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HSMM
Barcelos, 4750-275, Portugal
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Hospital Distrital de Santarém
Santarém, 2005-177, Portugal
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Hospital Leiria
Leiria, 2410-197, Portugal
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Hospital Pedro Hispano
Matosinhos Municipality, 4464-513, Portugal
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Hospital Prof. Dr. Fernando Fonseca
Amadora, 2720-276, Portugal
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