New hope for Hard-to-Treat breast cancer? study cut short

NCT ID NCT05954143

First seen Nov 20, 2025 · Last updated May 13, 2026 · Updated 18 times

Summary

This study tested a new drug called BDC-1001, given alone or with another drug (pertuzumab), in people with advanced HER2-positive breast cancer that had already been treated with several therapies, including trastuzumab deruxtecan. The goal was to see if the drug could shrink tumors. However, the study was stopped early after enrolling only 11 participants, so results are limited.

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Contacts and locations

Locations

  • City of Hope

    Irvine, California, 92618, United States

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Virginia Cancer Specialists

    Arlington, Virginia, 22205, United States

Conditions

Explore the condition pages connected to this study.