Sound waves punch holes in Brain's shield to attack deadly tumors

NCT ID NCT04528680

First seen Apr 25, 2026 ยท Last updated Apr 25, 2026

Summary

This trial tests a device implanted in the skull that uses ultrasound to temporarily open the blood-brain barrier, allowing chemotherapy drugs to reach brain tumors more effectively. About 57 adults with recurrent glioblastoma will receive this treatment after surgery to remove their tumor. The goal is to find a safe dose and see if this approach can shrink tumors and extend survival.

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Contacts and locations

Locations

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

Conditions

Explore the condition pages connected to this study.