Swallow a sponge, skip the scope: new test could spot esophagus condition
NCT ID NCT06803927
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a simple, non-invasive device called EndoSign, which is a sponge on a string that you swallow in a capsule. The sponge collects cells from the esophagus, which are then tested for signs of Barrett's esophagus, a condition that can lead to cancer. The results will be compared to standard endoscopy and biopsies. The trial involves 700 participants who either have Barrett's esophagus or are at high risk for it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
EndoSign Cell Collection Device (sponge on a string) with methylation biomarker test
What this could lead to
If successful, this could offer a simple, non-invasive way to screen for Barrett's esophagus, potentially catching it early and reducing the need for regular endoscopies.
What could go wrong
This is a diagnostic study, not a treatment. The test may not be as accurate as endoscopy, and results need further validation before widespread use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Gastroenterology Practice
RECRUITINGCordova, Tennessee, 38138, United States