Spit test could spot esophagus condition before it turns cancerous

NCT ID NCT05133102

Recruiting now Diagnosis Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking multiple saliva samples over time can better detect Barrett's esophagus, a condition where the lining of the food pipe changes and can raise the risk of cancer. About 275 adults who have had or will have an endoscopy will provide saliva samples. Researchers will analyze the bacteria in the mouth to see if a simple, non-invasive test can help diagnose this condition earlier.

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Conditions

The condition(s) this trial relates to.

Barrett esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARRETT ESOPHAGUS

Contacts and locations

Locations

Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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