Could a pill save insulin cells? new trial for kids and young adults with type 1 diabetes

NCT ID NCT07222332

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 6 times

Summary

This study tests whether baricitinib, a pill, can help preserve the body's ability to make insulin in people newly diagnosed with type 1 diabetes. About 300 children and young adults (ages 1 to under 36) will take either baricitinib or a placebo for 60 weeks. The goal is to see if the drug slows the loss of beta cells, which produce insulin, potentially reducing the need for insulin shots over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus type 1 diabetes mellitus 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 1

Contacts and locations

Locations

2Ca Braga
RECRUITING

Braga, 4710-243, Portugal
Abeno Medical Clinic
NOT_YET_RECRUITING

Osaka, 545-0052, Japan
Aberdeen Royal Infirmary
RECRUITING

Aberdeen, AB25 2ZN, United Kingdom
Addenbrooke's Hospital
RECRUITING

Cambridge, CB2 2QQ, United Kingdom
Akershus Universitetssykehus
RECRUITING

Lørenskog, 1478, Norway
Alberta Children's Hospital
NOT_YET_RECRUITING

Calgary, T3B 6A8, Canada
Alberta Diabetes Institute
NOT_YET_RECRUITING

Edmonton, T6G 2E1, Canada
Antwerp University Hospital
NOT_YET_RECRUITING

Edegem, 2650, Belgium
Asklepios Klinik Sankt Augustin
RECRUITING

Sankt Augustin, 53757, Germany
Assistance Publique - Hopitaux de Paris (AP-HP) - Hopital Robert Debre - Centre Hospitalo Universitaire (C -T
NOT_YET_RECRUITING

Paris, 75019, France
Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
NOT_YET_RECRUITING

Marseille, 13385, France
Austin Health - Repatriation Hospital
RECRUITING

Heidelberg West, 3081, Australia
Azienda Ospedale - Università Padova
NOT_YET_RECRUITING

Padova, 35128, Italy
Azienda Ospedale - Università Padova
NOT_YET_RECRUITING

Padova, 35128, Italy
Azienda Ospedaliera Universitaria Careggi
RECRUITING

Florence, 50134, Italy
Azienda Ospedaliera Universitaria Di Messina G. Martino
RECRUITING

Messina, 98125, Italy
Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento
RECRUITING

Verona, 37126, Italy
Azienda Ospedaliera Universitaria Meyer IRCCS
RECRUITING

Florence, 50139, Italy
Azienda Ospedaliero Universitaria Maggiore della Carità
RECRUITING

Novara, 28100, Italy
BC Diabetes Office
RECRUITING

Vancouver, V5Y 3W2, Canada
Barbara Davis Center for Childhood Diabetes
RECRUITING

Aurora, Colorado, 80045, United States
Birmingham Children's Hospital
NOT_YET_RECRUITING

Birmingham, B4 6NH, United Kingdom
CEDOES
RECRUITING

Vitória, 29055450, Brazil
CHU Rangueil
NOT_YET_RECRUITING

Toulouse, 31059, France
CHU UCL Namur/Site Sainte Elisabeth
NOT_YET_RECRUITING

Namur, 5000, Belgium
CHUL et Centre mère-enfant Soleil
NOT_YET_RECRUITING

Québec, G1V 4G2, Canada
CIUSSS- saguenay-Lac-Saint-Jean
NOT_YET_RECRUITING

Chicoutimi, G7H 5H6, Canada
CPCLIN
RECRUITING

São Paulo, 01228-200, Brazil
Cendi - Endocrinologia e Diabetes
RECRUITING

Goiânia, 74230-035, Brazil
Centre Hospitalier Sud Francilien
NOT_YET_RECRUITING

Corbeil-Essonnes, 91106, France
Centre Hospitalier Universitaire de Grenoble
NOT_YET_RECRUITING

Grenoble, 38700, France
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
NOT_YET_RECRUITING

Liège, 4000, Belgium
Centre for Children's Health Research
NOT_YET_RECRUITING

Brisbane, 4101, Australia
Centricity Research Ottawa LMC Endocrinology
RECRUITING

Ottawa, K2J 0V2, Canada
Centro De Diabetes Metabolismo E Endocrinologia
RECRUITING

Fortaleza, 60175-047, Brazil
Centro Materno Infantil do Norte
RECRUITING

Porto, 4050, Portugal
Centro de Diabetes Curitiba
RECRUITING

Curitiba, 80810-040, Brazil
Centro de Pesquisa Clínica de Marília - CPCLIM
RECRUITING

Marília, 17504-072, Brazil
Children's Hospital of Philadelphia (CHOP)
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Churchill Hospital
RECRUITING

Oxford, OX3 7LE, United Kingdom
Cliniques universitaires Saint-Luc
NOT_YET_RECRUITING

Brussels, 1200, Belgium
Clínica Hepatogastro JK
RECRUITING

São Paulo, 04077-020, Brazil
Diabeter - Rotterdam
RECRUITING

Rotterdam, 3011 TA, Netherlands
Diabetologikum Ludwigshafen/Die Praxis am Ludwigsplatz
RECRUITING

Ludwigshafen am Rhein, 67059, Germany
Driscoll Children's Hospital
NOT_YET_RECRUITING

Corpus Christi, Texas, 78411, United States
Fakultni nemocnice Ostrava
RECRUITING

Ostrava, 70852, Czechia
Hadassah Medical Center
RECRUITING

Jerusalem, 9112001, Israel
Hannoversche Kinderheilanstalt
NOT_YET_RECRUITING

Hanover, 30173, Germany
Helse Fonna - Haugesund Sjukehus
RECRUITING

Haugesund, 5528, Norway
Hopital Claude Huriez - CHU de Lille
NOT_YET_RECRUITING

Lille, 59037, France
Hospices Civils de Lyon - Hopital Louis Pradel
NOT_YET_RECRUITING

Bron, 69677, France
Hospital Clínic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Sant Joan de Déu
RECRUITING

Esplugues de Llobregat, 08950, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, 46026, Spain
Hospital Universitario Marqués de Valdecilla
RECRUITING

Santander, 39008, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitario Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hospital Universitário Maria Aparecida Pedrossian
RECRUITING

Campo Grande, 79080-190, Brazil
Hospital das Clinicas FMUSP
RECRUITING

São Paulo, 05403-000, Brazil
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFM -T
RECRUITING

Ribeirão Preto, 14051-140, Brazil
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08041, Spain
Hôpital Universitaire Necker Enfants Malades
NOT_YET_RECRUITING

Paris, 75015, France
IBTED - Tecnologia e Educação em Diabetes
RECRUITING

São Paulo, 04038-032, Brazil
Institute of Diabetes, Technology and Research - Clalit Health
RECRUITING

Herzliya, 4600201, Israel
Institute of Endocrinology and Metabolism named after Komissarenko
RECRUITING

Kiev, 04114, Ukraine
Instituto da Crianca com Diabetes
RECRUITING

Porto Alegre, 91350-250, Brazil
Instituto de Pesquisa Clinica
RECRUITING

São Paulo, 01223-001, Brazil
Ipswich Hospital
RECRUITING

Ipswich, 4305, Australia
Iuhw Ichikawa General Hospital
NOT_YET_RECRUITING

Ichikawa, 272-0824, Japan
Klinikum Karlsburg
NOT_YET_RECRUITING

Karlsburg, 17495, Germany
Kyiv City Endocrinological Center
RECRUITING

Kyiv, 01024, Ukraine
Linn Medical Center
RECRUITING

Haifa, 3515209, Israel
MTZ Clinical Research Powered by Pratia
RECRUITING

Warsaw, 02-172, Poland
Meir Medical Center
RECRUITING

Kfar Saba, 4428164, Israel
Milan Kvapil s.r.o., Diabetologicka ambulance
RECRUITING

Prague, 14900, Czechia
Nemocnice Jihlava
RECRUITING

Jihlava, 58633, Czechia
New Children's Hospital
NOT_YET_RECRUITING

Helsinki, 00029, Finland
OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces
RECRUITING

Barakaldo, 48903, Spain
Oslo Universitetssykehus Aker
RECRUITING

Oslo, 0316, Norway
Oslo Universitetssykehus Ullevål
RECRUITING

Oslo, 0450, Norway
Ospedale Pediatrico Salesi
NOT_YET_RECRUITING

Ancona, 60123, Italy
Ospedale San Raffaele
NOT_YET_RECRUITING

Milan, 20132, Italy
Oulun yliopistollinen sairaala
RECRUITING

Oulu, 90220, Finland
Perth Children's Hospital
RECRUITING

Perth, 6009, Australia
Pitie Salpetriere University Hospital
NOT_YET_RECRUITING

Paris, 75013, France
ProbarE i Lund AB
NOT_YET_RECRUITING

Lund, 222 22, Sweden
ProbarE i Stockholm AB
RECRUITING

Stockholm, 11437, Sweden
Quanta Diagnóstico e Terapia
RECRUITING

Curitiba, 80045170, Brazil
Queen Elizabeth Hospital Birmingham
RECRUITING

Birmingham, B15 2TH, United Kingdom
RED-Institut GmbH
RECRUITING

Oldenburg, 23758, Germany
Rabin Medical Center
RECRUITING

Petah Tikva, 4941492, Israel
Rambam Health Care Campus
RECRUITING

Haifa, 3109601, Israel
Royal Children's Hospital
NOT_YET_RECRUITING

Melbourne, 3052, Australia
Saitama Medical University Hospital
NOT_YET_RECRUITING

Iruma, 350-0495, Japan
Schneider Children's Medical Center
RECRUITING

Petah Tikva, 4920235, Israel
Schwerpunktpraxis für Diabetes Hormone & Stoffwechsel
RECRUITING

Hof, 95030, Germany
Sendai City Hospital - Asutonagamachi
NOT_YET_RECRUITING

Sendai, 982-8502, Japan
Sheba Medical Center
RECRUITING

Ramat Gan, 5262100, Israel
Shiga General Hospital
NOT_YET_RECRUITING

Moriyama, 524-8524, Japan
Shizuoka Children's Hospital
NOT_YET_RECRUITING

Shizuoka, 420-8660, Japan
Soroka Medical Center
RECRUITING

Beersheba, 8410101, Israel
Sourasky Medical Center
RECRUITING

Tel Aviv, 6423906, Israel
Southampton General Hospital
RECRUITING

Southampton, SO16 6YD, United Kingdom
Southern Adelaide Diabetes & Endocrine Services
RECRUITING

Oaklands Park, 5046, Australia
Southmead Hospital
RECRUITING

Bristol, BS10 5NB, United Kingdom
St. Joseph's Health Care
NOT_YET_RECRUITING

London, N6A 4V2, Canada
St. Olavs Hospital
RECRUITING

Trondheim, 7030, Norway
Stavanger Universitetssykehus
RECRUITING

Stavanger, 4011, Norway
Sydney Children's Hospital
RECRUITING

Randwick, 2031, Australia
TUM Klinikum
RECRUITING

München, 80939, Germany
Tallahassee Memorial HealthCare
NOT_YET_RECRUITING

Tallahassee, Florida, 32308, United States
Tampereen yliopistollinen sairaala
RECRUITING

Tampere, 33520, Finland
The Children's Hospital at Westmead
RECRUITING

Westmead, 2145, Australia
The Royal Melbourne Hospital
RECRUITING

Parkville, 3050, Australia
Turku University Hospital
RECRUITING

Turku, 20520, Finland
ULSAM - Hospital de Santa Luzia
RECRUITING

Viana do Castelo, 4900-858, Portugal
UMED Clinical Trials
RECRUITING

Lodz, 92-213, Poland
UZ Brussel
NOT_YET_RECRUITING

Brussels, 1090, Belgium
UZ Gent
RECRUITING

Ghent, 9000, Belgium
UZ Leuven
RECRUITING

Leuven, 3000, Belgium
Uddevalla Sjukhus
RECRUITING

Uddevalla, 451 53, Sweden
Unidade Local De Saude De Gaia/Espinho E.P.E.
NOT_YET_RECRUITING

Vila Nova de Gaia, 4434-502, Portugal
Universidade Federal do Rio de Janeiro
RECRUITING

Rio de Janeiro, 21941-590, Brazil
Universitaetsklinikum Ulm
RECRUITING

Ulm, 89075, Germany
Universitetssjukhuset Örebro
RECRUITING

Örebro, 701 85, Sweden
University Hospital of Wales
RECRUITING

Cardiff, CF14 4XW, United Kingdom
University of Naples Federico II
RECRUITING

Naples, 80131, Italy
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godinne
NOT_YET_RECRUITING

Yvoir, 5530, Belgium
Université Libre de Bruxelles - Hôpital Erasme
NOT_YET_RECRUITING

Brussels, 1070, Belgium
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu
RECRUITING

Wroclaw, 50-368, Poland
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-952, Poland
Vinnytsia Regional Clinical Endocrinology Dispensary
RECRUITING

Vinnytsia, 21010, Ukraine
Women's and Children's Hospital
RECRUITING

Adelaide, 5006, Australia
Yitzhak Shamir Medical Center
RECRUITING

Beer Yaacov, 70300, Israel
Zakarpattia Endoclinic
RECRUITING

Uzhhorod, 88000, Ukraine
Östersunds Sjukhus
NOT_YET_RECRUITING

Östersund, 831 31, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.