Can shedding pounds after breast cancer keep it away?

NCT ID NCT03946423

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study looks at whether weight-loss surgery (sleeve gastrectomy) combined with lifestyle changes, or lifestyle changes alone, can help women who have had early-stage breast cancer and are obese. The goal is to see if losing weight might lower the chance of the cancer returning. Participants are women who finished breast cancer treatment at least six months ago, have a BMI of 35 or higher, and are disease-free. The study first checks if women are willing to join and stick with the program for a year, with plans for a larger future trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sleeve gastrectomy (weight-loss surgery) and lifestyle intervention (counseling, diet, exercise)
What this could lead to
If successful, this could show that significant weight loss after breast cancer treatment reduces the risk of cancer coming back.
What could go wrong
This is a small feasibility study, not a large trial. It may not prove that weight loss prevents recurrence, and surgery carries risks like infection or complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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