Scientists probe why Weight-Loss surgery causes dangerous sugar drops

NCT ID NCT02823665

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at how gastric bypass and sleeve gastrectomy affect blood sugar control after eating. Researchers will give two drugs—Exendin-(9-39) and atropine—to understand the roles of hormones and nerves. The goal is to learn why some patients develop low blood sugar after surgery. The study involves 200 people, including those with and without post-surgery hypoglycemia, plus healthy volunteers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Exendin-(9-39) and Atropine

What this could lead to

If successful, this could reveal why some people develop low blood sugar after bariatric surgery and point toward better management strategies.

What could go wrong

This is an early-phase observational study, not a treatment trial. Results may not lead to new therapies, and findings may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dumping syndrome hypoglycemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • South Texas Veterans Health Care System

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Texas Diabetes Institute - University Health System

    RECRUITING

    San Antonio, Texas, 78207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact