Could a simple timing change improve treatment for kids with narrowed esophagus?

NCT ID NCT07100379

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at children born with esophageal atresia who develop narrowing (strictures) after surgery. Doctors use a balloon to stretch the narrowed area, but it's unclear how long the balloon should stay inflated. The trial will compare 30 seconds versus 180 seconds of inflation to see which reduces the need for repeat procedures over six months. About 128 children will take part across multiple centers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Endoscopic balloon dilation procedure

What this could lead to

If it works, this could help doctors choose the best inflation time to reduce the number of repeat dilation procedures needed for children with esophageal strictures.

What could go wrong

This is an early-stage study with only 128 participants, so results may not apply to all patients. The procedure itself carries risks like perforation or bleeding, and the optimal inflation time may not clearly improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal atresia esophageal atresia/tracheoesophageal fistula Esophageal Stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••