Esophageal atresia/tracheoesophageal fistula
MONDO:0008586A rare congenital, esophageal disorder characterized by an interruption in the continuity of the esophagus, with or without persistent communication with the trachea. The clinical presentation varies according to the anatomy, and can lead to the inability to swallow or, in the most severe cases, respiratory distress.
Also known as: Esophageal Atresia and/or Tracheoesophageal Fistula, TEF, esophageal atresia with or without tracheoesophageal fistula, te fistula, tracheoesophageal fistula, tracheoesophageal fistula with or without esophageal atresia
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Botox injection could replace surgery for Post-Esophagectomy stomach issues
Disease control Recruiting nowThis study tests whether a Botox injection into the stomach valve works as well as a surgical cut to prevent food from emptying too slowly after esophagus removal. About 170 adults having elective esophagectomy will be randomly assigned to one of the two procedures. Researchers w…
Phase: PHASE2, PHASE3 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Swallow a tiny magnet: painless camera could replace endoscopy
Diagnosis Recruiting nowThis study tests a magnetically controlled capsule endoscope—a tiny camera you swallow—to painlessly screen the esophagus and stomach. Researchers will compare different swallowing protocols to see which gives the best view of the Z-line and other areas. 300 patients already sche…
Sponsor: Bács-Kiskun County Teaching Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Could a simple timing change improve treatment for kids with narrowed esophagus?
Symptom relief Recruiting nowThis study looks at children born with esophageal atresia who develop narrowing (strictures) after surgery. Doctors use a balloon to stretch the narrowed area, but it's unclear how long the balloon should stay inflated. The trial will compare 30 seconds versus 180 seconds of infl…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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NIH launches massive GI data bank to fuel future discoveries
Knowledge-focused Recruiting nowThis study aims to collect medical data and biological samples (blood, urine, stool, and tissue) from up to 4,000 adults with known or suspected gastrointestinal diseases. Participants receive standard medical care at the NIH, and any extra samples or leftover tissue from procedu…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New study aims to sharpen diagnosis of swallowing disorders
Knowledge-focused Recruiting nowThis study compares two techniques—esophageal manometry and EndoFLIP balloon measurements—to evaluate how well they assess swallowing difficulties (dysphagia). Researchers will enroll up to 1,000 patients with known esophageal conditions to see how these measurements relate to sy…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Baby blood test may predict surgical recovery
Knowledge-focused Recruiting nowThis study measures two natural amino acids, arginine and ADMA, in newborns who had abdominal surgery within their first 5 days of life. Researchers want to see if the balance of these substances can help predict how quickly a baby recovers and whether complications arise. No ext…
Sponsor: Liverpool Women's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC