Viruses vs. infections: new hope for implant troubles?

NCT ID NCT07533292

Not yet recruiting Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether specially designed viruses, called bacteriophages, can eliminate persistent infections around orthopedic implants like hip or knee replacements. One hundred adults with such infections will receive the virus solution directly into the infected area after standard surgical cleaning. The main goal is to see if the bacteria are completely cleared, with a close watch on safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bacteriophage preparation (viruses that kill specific bacteria)
What this could lead to: If it works, this could offer a new way to treat hard-to-cure infections around joint replacements without relying on antibiotics.
What could go wrong: This is a single-center, early-phase trial with only 100 participants, so results may not apply broadly. The therapy may not clear the infection, and allergic reactions are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prosthesis-related infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMPLANT INFECTION ORTHOPEDIC

Contacts and locations

Locations

the Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China 310000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.