Engineered immune cells injected directly into the brain to fight childhood tumors
NCT ID NCT04185038
First seen Jan 10, 2026 · Last updated Apr 29, 2026 · Updated 13 times
Summary
This early-stage study tests a new treatment for children and young adults with aggressive brain tumors, including DIPG and other recurrent central nervous system cancers. The therapy uses the patient's own immune cells, which are modified in a lab to recognize and attack tumor cells. These engineered cells are delivered directly into the brain or spinal fluid through a small tube. The main goals are to see if this approach is safe and possible to do, and to learn how the cells move and work in the body.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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