New hope for tough leukemia: experimental drug AZD4512 enters human trials

NCT ID NCT07109219

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This study is testing an experimental drug called AZD4512, given alone or with other cancer medicines, in people whose B-cell acute lymphoblastic leukemia (B-ALL) has returned or stopped responding to standard treatments. The main goals are to check the drug's safety and find the best dose, and to see if it can shrink or control the cancer. About 83 participants aged 12 and older will take part across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Duarte, California, 91010, United States

  • Research Site

    WITHDRAWN

    Jacksonville, Florida, 32224, United States

  • Research Site

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Research Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • Research Site

    RECRUITING

    Franklin, Tennessee, 37067, United States

  • Research Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Research Site

    RECRUITING

    Melbourne, 3000, Australia

  • Research Site

    NOT_YET_RECRUITING

    Vancouver, British Columbia, V5Z 1M9, Canada

  • Research Site

    RECRUITING

    Toronto, Ontario, M5G 1X6, Canada

  • Research Site

    NOT_YET_RECRUITING

    Guangzhou, 510515, China

  • Research Site

    NOT_YET_RECRUITING

    Tianjin, 301600, China

  • Research Site

    RECRUITING

    Bunkyō City, 113-8677, Japan

  • Research Site

    RECRUITING

    Chūōku, 104-0045, Japan

  • Research Site

    RECRUITING

    Seoul, 03080, South Korea

  • Research Site

    RECRUITING

    Seoul, 06351, South Korea

  • Research Site

    RECRUITING

    Seoul, 06591, South Korea

  • Research Site

    RECRUITING

    Seoul, 3722, South Korea

  • Research Site

    NOT_YET_RECRUITING

    Badalona(Barcelona), 08916, Spain

  • Research Site

    RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    RECRUITING

    Salamanca, 37007, Spain

  • Research Site

    RECRUITING

    Santander, 39008, Spain

  • Research Site

    WITHDRAWN

    Valencia, 46026, Spain

  • Research Site

    RECRUITING

    Taichung, 40705, Taiwan

  • Research Site

    RECRUITING

    Taipei, 106, Taiwan

  • Research Site

    RECRUITING

    Bloomsbury, W1T 7HA, United Kingdom

  • Research Site

    RECRUITING

    Manchester, M20 4BX, United Kingdom

Conditions

Explore the condition pages connected to this study.