New hope for relapsed leukemia patients?

NCT ID NCT06137118

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 06, 2026 · Updated 34 times

Summary

This study tests a new drug, AZD0486, in teens and adults whose B-cell acute lymphoblastic leukemia (B-ALL) has come back or not responded to at least two prior treatments. The goal is to see if the drug is safe and can shrink or eliminate cancer cells. Because participants may need further treatment or monitoring, this is considered disease control, not a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
WITHDRAWN

Birmingham, Alabama, 35233, United States
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RECRUITING

Duarte, California, 91010, United States
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Los Angeles, California, 90048, United States
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Palo Alto, California, 94304, United States
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Tampa, Florida, 33612, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60637, United States
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New York, New York, 10016, United States
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Houston, Texas, 77030, United States
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Richmond, Virginia, 23298, United States
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WITHDRAWN

Seattle, Washington, 98109, United States
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Milwaukee, Wisconsin, 53226, United States
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Melbourne, 3000, Australia
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SUSPENDED

Porto Alegre, 90035903, Brazil
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São Paulo, 01401-002, Brazil
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São Paulo, 05652-900, Brazil
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Toronto, Ontario, M5G 2M9, Canada
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WITHDRAWN

Montreal, Quebec, H3T1C5, Canada
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WITHDRAWN

Montreal, Quebec, H4A 3J1, Canada
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RECRUITING

Changsha, 410008, China
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Chengdu, 610041, China
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Guangzhou, 510060, China
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Guangzhou, 510280, China
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Hangzhou, 310003, China
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Nanjing, 210008, China
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Nanjing, 210009, China
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Suzhou, 215004, China
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Tianjin, 300020, China
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RECRUITING

Zhengzhou, 450008, China
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SUSPENDED

Caen, 14033, France
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Marseille, 13009, France
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Nantes, 44000, France
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Paris, 75019, France
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Pierre-Bénite, 69495, France
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Toulouse, 31059, France
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Cologne, 50924, Germany
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Düsseldorf, 40225, Germany
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WITHDRAWN

Essen, 45147, Germany
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SUSPENDED

Frankfurt, 60590, Germany
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Freiburg im Breisgau, 79106, Germany
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Halle, 06120, Germany
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Hamburg, 20246, Germany
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Kiel, 24105, Germany
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München, D-81337, Germany
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SUSPENDED

Münster, 48149, Germany
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Würzburg, 97080, Germany
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Bergamo, 24127, Italy
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Bologna, 40138, Italy
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Monza, 20900, Italy
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Naples, 80123, Italy
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Roma, 00165, Italy
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RECRUITING

Bunkyō City, 113-8677, Japan
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Chiba, 260-8677, Japan
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Chūōku, 104-0045, Japan
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Fukuoka, 810-8563, Japan
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Kashiwa, 277-8577, Japan
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Kyoto, 606-8507, Japan
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Okayama, 701-1192, Japan
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Osaka, 545-8586, Japan
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Sapporo, 003-0006, Japan
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Toyohashi, 441-8570, Japan
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Yamagata, 990-9585, Japan
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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RECRUITING

Seoul, 6591, South Korea
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SUSPENDED

Barcelona, 08036, Spain
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Barcelona, 8035, Spain
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Madrid, 28025, Spain
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Madrid, 28046, Spain
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Salamanca, 37007, Spain
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ACTIVE_NOT_RECRUITING

Valencia, 46026, Spain
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SUSPENDED

Kaohsiung City, 833401, Taiwan
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SUSPENDED

Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan, 333, Taiwan
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London, EC1A 7BE, United Kingdom
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SUSPENDED

Manchester, M20 4BX, United Kingdom
Research Site
SUSPENDED

Surrey, SM1 2DL, United Kingdom

Conditions

Explore the condition pages connected to this study.

B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL) B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (B-ALL)