Tylenol vs. advil: which is safer for period cramps in Crohn's?
NCT ID NCT07337902
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study is testing how well two common pain relievers—acetaminophen (Tylenol) and ibuprofen (Advil)—work for period cramps in women with Crohn's disease. Twenty-four women will take each drug for two menstrual cycles and report their symptoms. The main goal is to see if a larger, more definitive study is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
acetaminophen and ibuprofen
What this could lead to
If successful, this pilot could pave the way for a larger study that helps determine which painkiller is safer and more effective for period cramps in women with Crohn's disease.
What could go wrong
This is a very small pilot study (24 people) focused on feasibility, not on proving which drug works better. Results may not apply to all women with Crohn's disease.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••