New pacing technique may protect heart function in AFib patients

NCT ID NCT07428967

Recruiting now Disease control Sponsor: St. Josefs-Hospital Wiesbaden GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of pacemaker placement after a procedure called AV node ablation for people with atrial fibrillation and normal heart function. One method uses standard right ventricular pacing, while the other targets the left bundle branch area. The goal is to see which approach better preserves the heart's pumping ability and improves quality of life. About 86 participants will be randomly assigned to one of the two pacing methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pacemaker implantation (left bundle branch area pacing vs. right ventricular pacing)
What this could lead to: If successful, this could offer a safer pacing method for people with atrial fibrillation, reducing the risk of heart muscle weakening after AV node ablation.
What could go wrong: This is a relatively small, early-stage trial (86 participants) comparing two procedures, so results may not apply to everyone. Both procedures carry standard risks of pacemaker implantation, such as infection or bleeding.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL ARRHYTHMIA ATRIAL FIBRILLATION

Contacts and locations

Locations

Evangelisches Krankenhaus Hagen-Haspe
NOT_YET_RECRUITING

Hagen, Germany
St. Josefs-Hospital Wiesbaden GmbH
RECRUITING

Wiesbaden, Germany

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