New cancer pill tested in humans – but trial halted early

NCT ID NCT05605119

First seen Apr 18, 2026 · Last updated Jun 19, 2026 · Updated 16 times

Summary

This early-stage trial tested an oral drug called AUR105 in 17 adults with advanced solid tumors or lymphomas that had not responded to prior treatments. The study aimed to find a safe dose and check how the drug moves through the body. However, the trial was terminated, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ALL India Institute of medical Scieneces

    New Delhi, New Delhi, 110029, India

  • All India Institute of Medical Sciences

    Bhubaneswar, Odisha, 751019, India

  • HCG City Cancer Center

    Vijayawada, Andhra Pradesh, 520002, India

  • IMS&SUM Hospital

    Bhubaneswar, Bhubaneswar, 751003, India

  • Kailash Cancer Hospital and Research Centre

    Vadodara, Gujarat, 391760, India

  • Krupamayi Hospital

    Aurangabad, Maharashtra, 431001, India

  • Moraya Multi-Speciality Hospital

    Pune, Maharasthra, 411033, India

  • Omega Hospitals

    Visakhapatnam, Andhra Pradesh, 530040, India

  • Sparsh Hospital and Critical Care

    Bhubaneswar, Odisha, 751007, India

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AUR105 (oral drug)

What this could lead to

If successful, this could point toward a new treatment option for advanced cancers that have stopped responding to other therapies.

What could go wrong

This is a very early, small Phase 1 trial (only 17 participants) that was terminated, so results are limited. The drug may not prove effective or safe in larger studies.

Conditions

The condition(s) this trial relates to.

Hodgkins lymphoma neoplasm non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.