Hidden kidney supercharge may undermine brain injury treatment

NCT ID NCT07410624

First seen Feb 15, 2026 · Last updated May 08, 2026 · Updated 8 times

Summary

This study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and remove medications from the body too quickly. It focuses on adults in the intensive care unit with life-threatening brain problems like stroke, severe injury, or infection. Researchers will collect urine and blood samples to measure kidney function and drug levels, aiming to find better dosing for antibiotics and seizure medicines.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UK HealthCare

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alberta Hospital

    RECRUITING

    Edmonton, Alberta, T6G 2X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.