Cold virus turned cancer killer enters human trials

NCT ID NCT06977737

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests ATTR-01, a modified cold virus designed to infect and multiply only in cancer cells, delivering an immune-boosting drug directly into the tumor. The study involves 72 adults with solid tumors who have not responded to standard treatments. The goal is to see if the virus is safe and can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ATTR-01 (a modified common cold virus that infects and kills cancer cells while delivering immune therapy)

What this could lead to

If successful, this could point toward a new treatment option for certain solid tumors that have not responded to standard therapies.

What could go wrong

This is the first human study, so safety and effectiveness are unknown. The trial is small (72 people) and early-stage, so results may not lead to a widely available treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • , St James' University Hospital

    RECRUITING

    Leeds, United Kingdom

  • Beatson West of Scotland Cancer Centre

    RECRUITING

    Glasgow, Scotland, United Kingdom

  • Churchill Hospital

    RECRUITING

    Oxford, United Kingdom

  • General Hospital San Pedro - START

    NOT_YET_RECRUITING

    Rioja, Spain

  • START Barcelona

    RECRUITING

    Barcelona, Spain

  • Start Fjd

    RECRUITING

    Madrid, Spain

  • Start Hm Ciocc

    RECRUITING

    Madrid, Spain

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, Wales, United Kingdom