Cold virus turned cancer killer enters human trials

NCT ID NCT06977737

Recruiting now Disease control Sponsor: Accession Therapeutics Limited Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests ATTR-01, a modified cold virus designed to infect and multiply only in cancer cells, delivering an immune-boosting drug directly into the tumor. The study involves 72 adults with solid tumors who have not responded to standard treatments. The goal is to see if the virus is safe and can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ATTR-01 (a modified common cold virus that infects and kills cancer cells while delivering immune therapy)
What this could lead to: If successful, this could point toward a new treatment option for certain solid tumors that have not responded to standard therapies.
What could go wrong: This is the first human study, so safety and effectiveness are unknown. The trial is small (72 people) and early-stage, so results may not lead to a widely available treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR, ADULT

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

, St James' University Hospital
RECRUITING

Leeds, United Kingdom
Beatson West of Scotland Cancer Centre
RECRUITING

Glasgow, Scotland, United Kingdom
Churchill Hospital
RECRUITING

Oxford, United Kingdom
General Hospital San Pedro - START
NOT_YET_RECRUITING

Rioja, Spain
START Barcelona
RECRUITING

Barcelona, Spain
Start Fjd
RECRUITING

Madrid, Spain
Start Hm Ciocc
RECRUITING

Madrid, Spain
Velindre Cancer Centre
RECRUITING

Cardiff, Wales, United Kingdom

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