Brain tumor combo shows promise in early trial

NCT ID NCT05345002

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tests a combination of two drugs—ATRA and retifanlimab—in people with a specific type of brain tumor (IDH-mutant glioma) that has returned after prior treatment. The goal is to see if this combo can shrink tumors or slow their growth by boosting the body's immune response. About 55 adults with recurrent astrocytoma or oligodendroglioma will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.