IDH MUTATION
Clinical trials for IDH MUTATION explained in plain language.
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New drug aims to keep aggressive bile duct cancer at bay after treatment
Disease control Recruiting nowThis study is testing whether a drug called ivosidenib can help prevent cancer from returning in people with a specific type of bile duct cancer who have already had surgery and chemotherapy. The trial will involve about 40 patients who have a particular genetic mutation (IDH1) i…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New drug duo aims to rally immune system against tough brain cancers
Disease control Recruiting nowThis study is testing whether combining an oral vitamin A-based drug (ATRA) with an immunotherapy (retifanlimab) can help control a specific type of recurrent brain tumor called IDH-mutant glioma. It aims to see if this combination is safe and can stimulate the patient's own immu…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Stephen Bagley, MD, MSCE • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Scientists test new Pill's journey to brain tumors
Knowledge-focused Recruiting nowThis early study is testing whether an experimental oral drug called DSP-0390 can reach brain tumors in sufficient amounts and affect tumor cell metabolism. Researchers will give the drug for about two weeks to 20 patients with specific types of brain tumors (grade II/III gliomas…
Matched conditions: IDH MUTATION
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC