New combo attack on lung tumors: immunotherapy, radiation, and surgery
NCT ID NCT06492954
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing whether combining an immunotherapy drug (atezolizumab) with targeted radiation and surgery is safe for people whose osteosarcoma has come back in the lungs. About 12 participants will receive the drug, radiation to one lung nodule, and then surgery to remove all visible lung tumors. The main goal is to find the safest dose and see if the combination can keep the cancer from growing for at least a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Atezolizumab (an immunotherapy drug that helps the immune system attack cancer cells)
What this could lead to
If this combination proves safe and effective, it could offer a new treatment option for people whose osteosarcoma has come back in the lungs, potentially helping to control the disease longer.
What could go wrong
This is a very early Phase 1 trial with only 12 participants, so it is primarily testing safety and dosing. The combination may not work better than existing treatments, and side effects from immunotherapy, radiation, and surgery could be significant.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chilldren's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact