Desperate measure: rerouting veins to save legs from amputation

NCT ID NCT06277362

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure that connects an artery to a vein in the foot to bring blood to tissues when standard treatments have failed. It includes 50 patients with severe leg artery disease and active wounds. The goal is to see if the procedure is safe and can prevent major amputation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

percutaneous deep foot venous arterialization procedure

What this could lead to

If it works, this could provide a way to save limbs and avoid amputation in patients with severe leg artery disease who cannot have standard treatments.

What could go wrong

This is an early study with only 50 participants, so results may not apply to everyone. The procedure carries risks like bleeding, infection, or failure to restore blood flow.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arcispedale Santa Maria Nuova

    WITHDRAWN

    Reggio Emilia, Italy, 42122, Italy

  • Azienda Ospedaliera S. Maria della Misericordia

    NOT_YET_RECRUITING

    Perugia, Perugia, 06156, Italy

    Contact

  • Irccs Inrca

    RECRUITING

    Ancona, Ancona, 60129, Italy

    Contact

  • Ospedale Bufalini

    RECRUITING

    Cesena, Italy, 47521, Italy

    Contact

    Contact

  • Ospedale Cardarelli

    RECRUITING

    Naples, Italy, 80131, Italy

    Contact

    Contact

  • Ospedale Pederzoli

    RECRUITING

    Peschiera del Garda, Veneto, 37019, Italy

    Contact Email: •••••@•••••

  • Ospedale San Martino

    RECRUITING

    Belluno, Italy, 32100, Italy

    Contact

    Contact

  • Ospedale Santa Chiara

    RECRUITING

    Trento, Italy, 38123, Italy

    Contact

    Contact

  • Ospedale di Conegliano - USLL2

    WITHDRAWN

    Conegliano, Italy, 31015, Italy