Implantable stimulator aims to stop blood pressure swings in spinal cord injury

NCT ID NCT07147296

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an implanted spinal cord stimulator (ARC-IM System) to help people with chronic spinal cord injury manage dangerously low blood pressure and fainting. Sixty participants will receive the implant and be randomly assigned to active or sham stimulation for 3 months, then all receive active therapy. The goal is to see if the device safely improves blood pressure stability and reduces symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ARC-IM System (implanted spinal cord stimulator)

What this could lead to

If it works, this could provide a long-term, at-home treatment to stabilize blood pressure and reduce fainting episodes for people with chronic spinal cord injury.

What could go wrong

This is a pivotal trial but still involves surgery and device risks. The control group receives a sham stimulation, and long-term benefits beyond 6 months are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Columbia University Irving Medical Center/ New York-Presbyterian Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Craig Hospital

    RECRUITING

    Englewood, Colorado, 80113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ICORD

    RECRUITING

    Vancouver, British Columbia, V5Z 1N1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • James J. Peters VA Medical Center

    RECRUITING

    The Bronx, New York, 10468, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kennedy krieger Institute

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shepherd Center / Emory University

    RECRUITING

    Atlanta, Georgia, 30309, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Spaulding Rehabilitation

    RECRUITING

    Cambridge, Massachusetts, 02138, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arkansas for medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UofL Health - Frazier Rehabilitation Institute

    RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Louisville

    RECRUITING

    Louisville, Kentucky, 40245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••