Spinal implant aims to stop dangerous blood pressure swings in paralyzed patients

NCT ID NCT07147296

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tests a device called the ARC-IM System, which is surgically implanted to help manage blood pressure instability in people with chronic spinal cord injury. The trial will enroll 60 adults who experience drops in blood pressure when sitting up. Participants will be randomly assigned to receive active therapy or a sham treatment for 3 months, after which everyone can receive the active therapy. The goal is to see if the device can safely reduce symptoms and improve blood pressure control.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center/ New York-Presbyterian Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Craig Hospital

    RECRUITING

    Englewood, Colorado, 80113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • James J. Peters VA Medical Center

    RECRUITING

    The Bronx, New York, 10468, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kennedy krieger Institute

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shepherd Center / Emory University

    RECRUITING

    Atlanta, Georgia, 30309, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Spaulding Rehabilitation

    RECRUITING

    Cambridge, Massachusetts, 02138, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arkansas for medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UofL Health - Frazier Rehabilitation Institute

    RECRUITING

    Louisville, Kentucky, 40202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Louisville

    RECRUITING

    Louisville, Kentucky, 40245, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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