New inhaled treatment aims to reduce need for breathing tubes in premature infants

NCT ID NCT06776783

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 27 times

Summary

This study tests an inhaled medication called APC-0101 in 520 premature babies born 26-33 weeks with breathing problems. The medication is given through a mask while babies are on breathing support. The goal is to see if it reduces the need for a breathing tube and liquid surfactant directly into the lungs. Babies are followed until they leave the hospital or reach 40 weeks adjusted age, with longer follow-up to 24 months.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advent Health

    RECRUITING

    Orlando, Florida, 32803, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Christus Children's Hospital

    RECRUITING

    San Antonio, Texas, 78207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Goryeb Children's Hospital

    RECRUITING

    Morristown, New Jersey, 07960, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jacobs Medical Center

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maria Farreri Children's Hospital

    RECRUITING

    Valhalla, New York, 10595, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Hospital of South Bend

    RECRUITING

    South Bend, Indiana, 46601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10461, United States

    Contact Email: •••••@•••••

  • The Trustees of Columbia University in the City of New York

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UF Health Jacksonville

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia School of Medicine

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Email: •••••@•••••

  • WVU Medicine Children's Hospital

    RECRUITING

    Morgantown, West Virginia, 26506, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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