New drug combo shows promise for rare salivary gland cancer
NCT ID NCT04325828
First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 24 times
Summary
This phase 2 study tests whether a combination of two hormone-blocking drugs (apalutamide and a GnRH agonist) can shrink or slow advanced salivary gland cancers that have a specific protein called the androgen receptor. About 31 adults with locally advanced or spread salivary gland cancer will receive the treatment. The main goal is to see how many patients have their tumors shrink or disappear.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aichi Cancer Center Hospital
Nagoya, 464 8681, Japan
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Hokkaido University Hospital
Sapporo, 060-8648, Japan
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Kansai Medical University Hospital
Hirakata, 573 1191, Japan
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National Cancer Center Hospital
Chūōku, 104 0045, Japan
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National Hospital Organization Kyushu Medical Center
Fukuoka, 810 8563, Japan
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National Hospital Organization Shikoku Cancer Center
Matsuyama, 791 0280, Japan
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Niigata University Medical And Dental Hospital
Niigata, 951 8520, Japan
Conditions
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