Antibiotics after bladder botox: infection prevention or not?

NCT ID NCT04444440

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether taking the antibiotic ciprofloxacin for three days after bladder Botox injections reduces the risk of urinary tract infections in women with overactive bladder. About 202 women will be randomly assigned to receive either the antibiotic or a placebo pill. The main goal is to see if fewer infections occur in the antibiotic group over six weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ciprofloxacin (antibiotic)

What this could lead to

If it works, this could show that a short course of antibiotics after bladder Botox reduces the chance of urinary tract infections in women.

What could go wrong

This is a Phase 4 trial, but it only looks at infection rates, not long-term safety. Antibiotics can cause side effects like nausea, and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bacterial urinary tract infection overactive bladder urinary tract infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Urogynecology Clinic - Royal Alexandra Hospital

    RECRUITING

    Edmonton, Alberta, T5H3V9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact