ICU study checks if blood filters zap Life-Saving antibiotics

NCT ID NCT07230041

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a blood-filtering cartridge (HA 380) used with continuous kidney dialysis removes antibiotics in ICU patients with septic shock and kidney failure. Researchers will take blood samples before and after the filter at several time points to measure changes in antibiotic levels. The goal is to understand drug loss so doctors can better dose antibiotics in these critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hemoadsorption cartridge (HA 380) and continuous renal replacement therapy

What this could lead to

If successful, this study could help doctors adjust antibiotic doses more accurately for ICU patients on blood purification, improving treatment effectiveness.

What could go wrong

This is a very small, early observational study with only 20 participants. It measures drug levels but does not test any new treatment or patient outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Niguarda Hospital

    RECRUITING

    Milan, Italia, 20162, Italy