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Can the Brain's Information-Integration process explain Anorexia's grip?

NCT ID NCT02381639

Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Researchers at Nantes University Hospital are studying central coherence, the brain's ability to pull complex information into a coherent whole, in women with restrictive anorexia nervosa. The study compares patients in the active phase of the illness with healthy volunteers. All participants complete a 90-minute session of cognitive tests and self-assessment questionnaires. The goal is to understand whether differences in central coherence relate to the disorder and could inform future cognitive remediation therapies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a 90-minute interview combining cognitive tests and self-assessment questionnaires
What this could lead to
If researchers find a link between central coherence and anorexia nervosa, it could point toward cognitive remediation therapies that target this thinking process.
What could go wrong
This is an observational study with no treatment, so it cannot prove that central coherence problems cause or maintain anorexia. The findings may not apply to men or to people outside this single hospital in Nantes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

122 people

The number who actually took part.

Started

Jun 2015

Finished

Aug 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * For the patients : * Woman. * Aged of more than 15 years and 3 months. * Followed in the addiction service of the University Hospital of Nantes (consultations and / or hospitalizations) for Restrictive Anorexia Nervosa (according to the diagnostic criteria of DSM-IV-TR). * French language mastered. * Having signed the consent if major and if not the legal representatives have signed the consent (for minors). * For the volunteers : * Women. * Aged of more than 15 years and 3 months. * French language mastered. * Having signed the consent if major and if not the legal representatives have signed the consent (for minors). Exclusion Criteria: * For the patients : * Man * Age under 15 years and 3 months old * Current Renutrition by nasogastric tube * Personal history of: * Head injury, neurodegenerative diseases, epilepsy unbalanced, unbalanced endocrine disorder, mental retardation * Support for current or past cognitive remediation * Opposition of the patient and / or his legal representatives if minor * Subject under legal guardianship * Current participation or in the past to pharmacological research protocol (time since the end of their participation in the protocol less than one year) * French language not mastered * For the volunteers : * Man * Age under 15 years and 3 months old * Current Renutrition by nasogastric tube * Personal history of: * Eating disorders * Head injury, neurodegenerative diseases, epilepsy unbalanced, unbalanced endocrine disorder, mental retardation * Support for current or past cognitive remediation * Opposition of the volunteer and / or his legal representatives if minor * Subject under legal guardianship * Current participation or in the past to pharmacological research protocol (time since the end of their participation in the protocol less than one year) * French language not mastered

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Conditions

The condition(s) this trial relates to.

anorexia nervosa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa

Contacts and locations

Locations

  • CHU de Nantes, Service d'Addictologie

    Nantes, France

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