Can a simple blood draw reduce transfusions in bone cancer surgery?
NCT ID NCT06459141
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a technique called acute normovolemic hemodilution (ANH) in 150 adults undergoing bone tumor surgery. Before surgery, some blood is removed and replaced with fluid, so that if bleeding occurs, the patient loses less red blood cells. The goal is to see if this reduces the need for donor blood transfusions during surgery, which could lead to fewer complications and faster recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
acute normovolemic hemodilution (a procedure where some blood is removed and replaced with fluid before surgery to reduce the need for donor blood)
What this could lead to
If it works, this could provide a safer way to manage blood loss during bone tumor surgery, reducing the need for donor blood transfusions and their associated risks.
What could go wrong
This is a small, early-stage trial (150 participants) and previous studies have shown mixed results. The procedure may not significantly reduce transfusions or could carry its own risks.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Second Affiliated Hospital of Zhejiang University anesthesiology department
RECRUITINGHangzhou, Zhejiang, 310000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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