Could a simpler antibiotic be just as good for older pneumonia patients?

NCT ID NCT06229288

First seen Dec 08, 2025 · Last updated May 14, 2026 · Updated 20 times

Summary

This study tests whether a narrow-spectrum antibiotic (amoxicillin alone) works as well as a broader one (amoxicillin/clavulanate) for pneumonia in people aged 65 and older who are hospitalized but not in intensive care. The goal is to reduce unnecessary use of strong antibiotics, which can cause side effects and lead to drug resistance. About 326 participants will be randomly assigned to one of the two treatments, and researchers will check if the simpler option is just as effective at curing the infection by day 30.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assistance Publique Hopitaux De Marseille

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Perigueux

    RECRUITING

    Périgueux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Saint-Nazaire

    RECRUITING

    Saint-Nazaire, France, 44600, France

  • CH Saint-Nazaire

    RECRUITING

    Saint-Nazaire, France, 44600, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHD Vendée

    RECRUITING

    La Roche-sur-Yon, France

  • CHD Vendée

    RECRUITING

    La Roche-sur-Yon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU - TOULOUSE Hôpital Purpan

    RECRUITING

    Toulouse, France

  • CHRU - TOULOUSE Hôpital Purpan

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU Brest

    RECRUITING

    Brest, France

  • CHRU Brest

    RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU TOULOUSE - Hôpital Rangueuil

    RECRUITING

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Angers

    RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Avicenne AP-HP

    RECRUITING

    Bobigny, France

  • CHU Avicenne AP-HP

    RECRUITING

    Bobigny, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Grenoble-Alpes

    RECRUITING

    La Tronche, France

  • CHU Grenoble-Alpes

    RECRUITING

    La Tronche, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Nantes

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier Bretagne Atlantique

    RECRUITING

    Vannes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chu Angers

    RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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