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Smart software aims to perfect antibiotic dosing in septic shock

NCT ID NCT04178148

Completed Disease control Sponsor: Centre Hospitalier Universitaire de Nīmes Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a computer program called BestDose could help doctors give the right amount of the antibiotic amikacin to patients with septic shock. The goal was to get drug levels in the ideal range after the second dose. 180 patients took part, and researchers checked if more patients reached target levels with the software's help.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
amikacin
What this could lead to
If successful, this approach could help doctors give the right dose of amikacin to septic shock patients more reliably, potentially improving survival.
What could go wrong
This is a completed early-stage study with 180 patients. The software may not work for all patients, and better drug levels don't guarantee better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SHOCK, SEPTIC

Contacts and locations

Locations

  • CHU de Nimes

    Nîmes, 30029, France

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