New PET tracers tested to spot Alzheimer's tau tangles

NCT ID NCT05464368

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests three new imaging agents (18F-RO948, 18F-MK6240, and 18F-GTP1) to see how well they detect tau protein buildup in the brains of people with Alzheimer's disease compared to healthy older adults. About 38 participants aged 50-100 will receive PET scans to compare these tracers. The goal is to improve diagnosis by finding which tracer works best and has fewer false signals.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States